How does Vibrance and L Arginine work?

By Dr. Elizabeth Knepp

How does Vibrance work

This cream is a female personal care product that allows women to safely and effectively manage the negative effects of sexual dysfunction symptoms. It is targeted at women over the age of thirty (30), the point at which such symptoms are felt to begin.

The patent pending cream works by combining a nitric oxide producer (L-Arginine) with antioxidants to dilate the blood vessels of a woman’s genitalia, thereby increasing blood flow, sensitivity and lubrication during sexual activity and stimulation.

The cream is a unique product distinct from other preparations using Arginine to promote vasodilatation. This is due to a proprietary modification made to the Arginine molecule, which removes the electrical charge normally attached to the molecule. This allow the Arginine to be absorbed through the skin and makes it far more effective than any other Arginine product.

A placebo controlled double blind study of this cream has been conducted in Pittsburgh PA with the conclusions as follows:- “a significant improvement in sexual response with the topically applied proprietary modification of the L-Arginine was demonstrated”

It continues further stating “This study demonstrated that topically applied L-Arginine ethyl ester cream in a aquaphor base does enhance sexual response significantly more than a placebo with no reported side effects.

What is L Arginine?
The active ingredient in the cream is L Arginine ethyl ester. L Arginine is a natural amino acid found in most protein containing foods such as meat and fish. The ethyl ester side of the chain was added to increase the effectiveness of the product. The
important question is “what happens to L Arginine ethyl ester once applied?” L Arginine ethyl ester is broken down in L Arginine, a naturally occurring amino acid, and ethanol by the enzyme arginase which is found in all tissues. The minute
amounts of ethanol, which cannot even be detected by blood tests, are broken down by alcohol dehydrogenase in the same pathway that alcoholic beverages are metabolized yielding sugar, water and carbon dioxide. The L Arginine molecule enters the citrulline pathway and is converted to Nitric oxide which acts at the level of blood vessels to cause increased blood flow.

The science behind this cream is well understood. When a woman is sexually stimulated, her brain signals the arousal nerves and the Nitric Oxide Synthesis System is activated. The Nitric Oxide Synthesis System converts available L-Arginine into Nitric Oxide. The Nitric Oxide draws blood into the area causing the clitoris to become aroused and highly sensitive.

The cream uses a unique derivative of L-Arginine, which allows for delivery, without the associated negative side effects of similar products.

This proprietary formula allows for topical application thus avoiding any potentially harmful or annoying side effects that are seen with oral medications. Furthermore, the topical application can be incorporated into the lovemaking process allowing for a more spontaneous experience. Application of the cream results in a warm, tingling sensation due to blood engorgement and increased lubrication. This is not the case with pills such as Viagra™ or other supplements, which must be taken at a pre-determined time period in anticipation of a sexual encounter.

Why is it better than other creams?

To address the question of as to why this cream rather than the rest, the effectiveness of this cream lies in the proprietary formulation that allows for a much better delivery of the L-Arginine. Without this formulation, L-Arginine on its own is unable to be
truly effective.

In order for our competition to achieve some measure of an arousal response they must rely on the addition of nitrate, salicylates or other irritants such as Camphor, Menthol or Phenols to agitate the area in question. The advantage of this cream
over other female arousal cream products is its ability to deliver results WITHOUT the use of menthol or propylene glycol
(irritants).

Menthol when applied topically is a skin irritant and like other menthol containing creams gives a sensation of warmth without causing vasodilatation. Menthol must be added to these other preparations because the standard L-Arginine is not efficiently or effectively delivered.

Last updated: 08 June 2006

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